Q and A: Can My Villain Cook Attempt a Murder Using Contaminated Food?

02 Feb

Q: My villain is a cook and he wants to kill the hero by feeding him tainted food. I want to avoid using a detectable poison, so I thought a deliberately introduced food-borne pathogen, such as ptomaine, botulism, E.coli, or salmonella, or something like those, would do it. But how do I get the bacteria/germs/whatever in the food? What will it do to him? How long would it take him to die, and what steps could the hero take to make sure he survives? What could the villain do to make sure the hero dies?


E. Coli

E. Coli Growing on a Culture Plate


A: This scenario will work but there are a few problems with it. First of all, using bacteria for murder is extremely unpredictable and most killers prefer a more predictable method. Just because your villain feeds contaminated food to the victim it does not mean that he will die because contaminated food rarely kills people but rather merely makes them sick. Typically people survive these types of illness—but not always. The best way to assure, or at least increase the probability, that your victim would die is to prevent him from reaching medical care.

Infectious processes most often kill by two mechanisms. The first is that they alter the function of the infected organ. For example, pneumonia can kill by infecting the lungs and filling the air spaces with bacteria and liquids we call exudates. This is simply the body’s reaction to the infection. Like a weeping wound or one that forms pus. This is what happens in the lungs and if so it interferes with the exchange of oxygen and the victim can die because the lungs fail. An infection in the kidneys can do the same thing by causing kidney failure and infection in the gastrointestinal tract, which is what would most frequently happen with ingested bacteria, can lead to severe diarrhea and dehydration or in some cases or severe bleeding and death can follow from shock.

But the most treacherous thing associated with any of these infections is the passage of the bacteria from the infected organ into the bloodstream. We call this sepsis or septicemia, big words that mean infection in the blood stream. When this happens the infection spreads rapidly throughout the body and very quickly the victim can suffer from septic shock–low blood pressure and shock from bacteria in the blood stream. This can lead to death in short order.

So regardless of which bacterium you decide to use, it would need to be added to the food and the victim ingest it. This would make him ill with gastrointestinal symptoms such as nausea, vomiting, diarrhea, abdominal pain, and perhaps bleeding in either the diarrhea or the vomiting. If untreated such an infection could then spread to the bloodstream and be deadly. But the key here is that he must be prevented from reaching medical help. Otherwise he would be treated and survive. But untreated his chance of survival is dramatically reduced. So you need to figure a way to prevent him from reaching medical care once he developed symptoms.

As for what bacteria to use, both ptomaine and botulism would be very difficult to come by. They are rare and your cook would have no access to this type of organism. He could of course damage a can of some food product and leave it sitting in a warm environment and hope that the right bacteria grew but most likely it would not be the bacterium that causes botulism. That’s actually quite rare. So there would be no way for him to predict what organism would occur under that circumstance.

On the other hand, things such as E. coli, Salmonella, and Shigella are quite common causes of food-borne gastrointestinal illness. If your chef knew someone who was infected with one of these, perhaps from a recent trip to Mexico where these are not uncommonly encountered, he could then use this individual to supply the needed bacteria. How would he do this? The best way would be to obtain some stool from the infected individual. This could be from contaminated toilet paper or an un-flushed toilet. Gross but that’s the way it is. This could then be placed into some food product and allowed to grow, which he could simply do a closet at home. He could then add some of this bacterial soup to the food product and in this way introduce a large amount of bacteria to the victim. Even better would be if he could find a way to inject this intravenously into the victim but that’s not absolutely necessary.

Again, this would make the victim very ill with gastrointestinal symptoms. Then, as I said, you’ll need to devise some scenario that prevents him from reaching medical help and if so he could easily die from sepsis.

There is an excellent non-fiction book in which a murder is committed exactly like this. It involves the murder of Joan Robinson Hill by her husband Dr. John Hill. It took place in the 1960s in Houston Texas and is an incredible story. The book is titled Blood and Money and was written by Tommy Thompson. If you can a copy of this it might help. Dr. Hill apparently grew bacteria in petri dishes at home and infected cream puffs to kill his wife. He then admitted her to a small hospital in the outskirts of Houston and he managed her care, which amounted to preventing her from getting adequate treatment since he did not offer her the treatment she needed. It became a huge and convoluted case that did indeed involved blood and money.


17 responses to “Q and A: Can My Villain Cook Attempt a Murder Using Contaminated Food?

  1. Sue Coletta

    February 2, 2016 at 2:35 pm

    Fascinating. Adding Blood and Money to my TBR pile.


    • D.P. Lyle, MD

      February 2, 2016 at 2:38 pm

      You’ll love. It’s a Texas story all the way. I knew some of the folks involved and worked with them in my training at TX Heart Inst. Tommy is no longer with us but he also wrote a great book called HEARTS about the feud between heart surgeons Denton Cooley and Michael DeBakey. Fascinating story also.

      Liked by 1 person

  2. Cheryl B. Dale

    February 2, 2016 at 2:48 pm

    Good to know!



    February 2, 2016 at 2:56 pm

    Another way it could work is if the would-be victim is immune-compromised for some reason. So their bodies are less able to tolerate the pathogens. Could be a lifelong condition or the recipient of certain types of medical care (cancer treatment, kidney transplant) that has either temporarily or permanently damaged their immune system.


  4. Richard Mabry

    February 2, 2016 at 3:05 pm

    I was familiar with the Blood and Money case, but had forgotten about the book. I’ll look for it. Thanks for the reminder.


  5. Teresa Reasor

    February 2, 2016 at 3:27 pm

    I’ve read Blood and Money and I even remember the movie with Sam Elliot and Farah Fawcett.
    Thank you so much for all this information. It definitely makes my imagination run wild. And is always helpful.


  6. Heidi Wilson

    February 3, 2016 at 4:56 am

    A wonderful murder-by-food-poisoning mystery is Malice Aforethought by Francis Iles. Back in the 1930s, when it takes place, people died of botulism much more often. The ironic twists and turns by which the murderer gets his desserts make for a wonderful ending.


  7. Elaine Abramson

    February 3, 2016 at 11:53 am

    Another way to have a compromised immune system is to have your spleen removed. Mine was removed when I was six years-old. Ever since then I have had problems in which I easily pick up one illness after another and take twice as long as the average person to heal. Their are several ways one can lose a spleen – car accident, child abuse, and removal to prevent the spread of cancer.


    • D.P. Lyle, MD

      February 3, 2016 at 12:03 pm

      True–though the compromise is often minimal. But the earlier the age that it is removed the greater the impact as the spleen is involved in forming the overall immune system as we develop. Later in life the impact is less. But at 6 it would make a difference. Thanks for your post.


  8. Ray Peden

    February 3, 2016 at 11:55 pm

    Doug, this is not a comment on this post but to let you know that I published my first novel, One Tenth of the Law, a few months ago and since you offered much appreciated advisory input I’d like to send you a copy. (It’s a good read, by the way, or so I’m told.) You have an address? Let me know at


  9. Anne Louise Bannon

    February 4, 2016 at 2:28 pm

    There was another book that used botulism (the title of which I am blanking on) as the toxin. The interesting thing about that one is that the killer had done some home canning and unintentionally got a bad batch, and thus knew she had a weapon and then took advantage of it. Yeah, botulism is rare (thank God), but it does happen and it does kill relatively quickly, especially if the team in the Emergency Department doesn’t know what it’s looking for.


  10. alan ward

    October 2, 2017 at 4:33 am

    A murderer cook can use filthy water I.e.water from drains and sewage water plus he can also add saliva of stray dogs which means it is heavily contaminated with deadly microbes and add it to the juice or food of the victim .That I think will kill the hero within very less time…..that can be a perfect murder…won’t it be Lyle sir.


    • D.P. Lyle, MD

      October 2, 2017 at 7:41 am

      It could but it might simply make them sick with a GI infection—nausea, vomiting, diarrhea—or it might not make them sick at all. Folks eat all sorts of contaminated stuff and come away just fine. Or they get very sick and die—as you say. So it’s very unpredictable and killers like more predictability. That’s why those that contaminate food usually reach for a poison of some type.


      • Rohit kumar

        December 19, 2017 at 9:36 am

        1)What if the murderer cook goes to a hospital and finds patient’s suffering from meningitis or tuberculosis…. He offers them water….obviously the germs from their mouth will get added to water…if these germs are in large amounts they can cause these diseases….so the person will become very sick….maybe they will die….even if they survive the murderer cook can again add these germs to his food….that I believe will kill them….. 2) second scenario can be why would he add these bacteria to his food….what if he directly injects them into the victims do that he will have to make his victim unconscious first….that he can do using a sleeping drug…..first make them unconscious and then inject them with bacteria….that will cause sepsis and the victim will die.he can also do this using lancet’s infecting them with bacteria. This method can work I believe…


      • D.P. Lyle, MD

        December 19, 2017 at 9:39 am

        Either os these could work–or not. It’s unpredictable.



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