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Author Archives: D.P. Lyle, MD

About D.P. Lyle, MD

Author, Lecturer, Story Consultant

What Killed the Aztecs? Lessons From Typhoid Mary.

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History tells us that in 1519 Hernando Cortes reached the shores of Mexico where he encountered the Aztecs. It has been estimated that around 25 million Aztecs existed at that time. But the arrival of the conquistadors changed everything. History also indicates that two epidemics, one in the 1540s and the other in the 1570s, crippled, essentially destroyed, the Aztec Empire. It is estimated that 10 to 20,000,000 Aztecs succumbed to some form of infectious process.

The Aztecs called these epidemics cocoliztli, their word for pestilence. Historians have long argued about what caused this horrific outbreak. At various times, researchers have suggested that the culprit was measles, mumps, smallpox, and several other disorders.

It’s important to note that epidemics of this size occur when an organism is introduced into a population that has no immunity to it. The Aztecs had never confronted such infectious agents and therefore had no individual or community resistance. The same thing happened in Europe when the Plague made its appearance. The most famous of these epidemics we call The Black Death. It killed millions and changed history. Same was true for the Aztecs.

But what exactly happened?

A new study suggests that the pathogen responsible just might be Salmonella, specifically S. Paratyphi C. DNA analysis indicates that this organism can be traced back to Europe and might indeed have traveled in the bodies of the conquistadors and infected the unprotected Aztec population. More research is needed but this is an intriguing development.

You’ve heard of salmonella I’m sure. It’s occasionally picked up in contaminated food and water by travelers to foreign countries and on some occasions. it can become a devastating illness and can even be deadly. A famous US epidemic occurred in the early 1900s when Mary Mallon, a healthy carrier of the organism and a cook, spread typhoid to numerous people. She became known as Typhoid Mary and her story is very interesting. Typhoid is caused by the organism Salmonella typhi, which places it in the same family as the organism that might have taken down the Aztec Empire.

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TYPHOID MARY

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Posted by on September 28, 2017 in Cause & Manner of Death, Medical History

 

Beware: Health Food Can Kill You

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Aconite, also known as monkshood or wolfsbane, is beautiful and looks harmless. Not true. It’s a deadly poison. When ingested, it has potentially deadly cardiotoxic and neurotoxic effects. Its most often kills through the generation of deadly changes in the cardiac rhythm. Victims suffer shortness of breath, palpitations, chest pain, numbness and tingling of the face and other body parts, nausea, and ultimately paralysis, cardiac arrest, and sudden death. Pleasant, huh?

Aconite is easily available, not only at your local nursery but also at various health food stores where it comes in many varieties, including herbal teas. Several recent poisonings related to an aconite-containing herbal tea sold by a San Francisco company show how dangerous this chemical can be. Of course, other health food stores sell aconite and you can easily buy it on the Internet.

I always tell my patients that the second most dangerous place on earth, after a aircraft carrier deck during flight operations, is a health food store. Though most of the products they sell are mostly harmless, and mostly not helpful, some are downright deadly. Many years ago there was a Ma Huang crisis in that several people died from taking supplements laced with this material. Ma Huang is basically an amphetamine and, like aconite can cause deadly cardiac arrhythmias as well as a marked elevation of blood pressure and strokes.

The point is, none of these are regulated. The FDA, for all its warts, does indeed protect consumers. It’s very difficult to create, test, and bring a new drug to market. It cost billions and takes many years, sometimes more than a decade. The FDA requires strict proof that the medicine actually does what it’s designed to do and that its side effects and toxic potential are acceptable and well understood. This is not the case in products you buy at your local health food store. Many are mixed up by a guy named Joe in his garage in a cat box. Trust me, Joe is not a chemist, or a pharmacist, and he possesses no medical training. He might not even have a GED. But he can mix up some cool stuff and put it in fancy packaging and make it look real. And safe. And it might be. But of course, it might not.

The take-home message here is that do not accept the packaging, the product description, or its prime location at eye level on the display rack. Do your research. Find out what’s really inside and what its toxic potential is. And do not buy anything from a guy named Joe.

 

Bugging Your DNA

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Everybody hates mosquitoes. They irritate, they bite, and they carry disease. In fact they are likely the most deadly creature on Earth since they spread malaria through many regions of the world. They also spread things like yellow fever and Zika – – – and a host of other nasty little problems.

But can mosquitoes place you at a crime scene? If so, how would this work?

Let’s say investigators come to a murder scene and find a smashed and dead mosquito on the bed sheets near the corpse. It might be reasonably assumed that this mosquito bit someone and that person then killed it, leaving it where it fell. Could that be used to ID the killer?

It appears that human blood can remain in the mosquito’s stomach for up to two days. And if this is extracted, it can be used in DNA profiling. So the mosquito at the crime scene could be collected and tested, and if DNA were found, a profile could be generated and lead back to the killer.

Esoteric, but fascinating.

 
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Posted by on August 31, 2017 in Crime Scene, DNA, High Tech Forensics

 

Holmes, Thorndyke, Locard, Gross, and the Modern CSI

There are no bigger names in the history and development of modern crime scene investigation than French investigator Edmond Locard and his Austrian counterpart Hans Gross. These two men shaped the development of crime scene investigation and even today their techniques create the cornerstone of forensic science. Locard’s Exchange Principle underlies every forensic technique.

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EDMOND LOCARD

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HANS GROSS

They were also great fans of Sir Arthur Conan Doyle’s Sherlock Holmes and R. Austin Freeman’s Dr. John Evelyn Thorndyke. Locard even suggested that students of police procedure read the Sherlock Holmes stories and learn from his techniques.

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Both the real-life investigators and the fictional ones had one thing in common: the careful and meticulous approach to any crime scene, taking care to collect all useful evidence, while not damaging or contaminating it.

In my book Forensics For Dummies, the methods and techniques used to evaluate a crime scene and collect evidence are explained in great detail. Check it out if you want to know more about the techniques that saw their origin more than 100 years ago.

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DNA Solves the 80-Year-Old Death of Belgium’s King Albert I

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Belgium’s King Albert I was found dead on February 17, 1934. The experienced rock climber was found at the base of a large formation with a gash to his head. Speculation that he was murdered ran rampant. During World War I, he had resisted Germany and attempted to block German troops from entering his country. They eventually did, but he fought them every step of the way. Was Germany somehow complicit in his untimely death?

Many felt that he had been killed elsewhere and his body dumped where it was found. The evidence suggested otherwise. His glasses were found nearly 40 feet above him – – he was very far-sighted – – and his climbing rope was still attached to his body. But, the most important evidence that suggested a fall rather than a murder was blood on the leaves near the King. If this blood was indeed Albert’s, then he must have shed it at that location, meaning he was at least briefly alive when he reached the ground at the base of the rock formation. If he had been killed elsewhere and dumped, there would have been no blood around the body. Dead folks don’t bleed. The leaves were apparently collected and preserved.

Flash forward to 2014. The blood of the leaves was tested. Not only was it human blood and but also it was matched against two relatives of the King. These results suggested that the blood was indeed the King’s blood and it had likely been shed from a head injury he received from his fall. This 80-year-old “murder” case seems to be a tragic accident.

 

Peanut Butter Can Kill You

 

Peanut butter can be deadly. If you’re allergic to peanuts.

Our immune system protects us from all sorts of bad things – – bacteria, fungi, and viruses. Our bodies recognize these foreign invaders and the immune system immediately goes to work manufacturing antibodies against the intruders. These antibody signal for help and pretty soon white blood cells show up along with their buddies known as mast cells. These cells release an array of chemicals that help damage the invaders, which are then consumed by the white blood cells. And life goes on.

But sometimes the immune system overreacts. It produces a massive amount of chemicals that can cause a drop in blood pressure, a tightening of the bronchial tubes, a leaking of fluids within the tissues and, most deadly, the lungs. We call this overwhelming reaction anaphylaxis. It is typically immediate and severe.

Such a reaction happened to Miriam Ducre-Lemay. She was allergic to peanuts. Her boyfriend had apparently eaten a peanut butter sandwich and had given her a good night kiss. Then everything went off the rails. She suffered an acute anaphylactic reaction and by the time paramedics arrived it was too late. This illustrates that it only takes a very small amount of an antigen (in this case the peanut oils in the peanut butter) to initiate a severe anaphylactic reaction.

 

In the 1800s, Wagon Train Travel Could Be Deadly

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Many brave souls headed West during the 1800’s, often by wagon train. They fought weather, disease, starvation, hostile folks of all types, and potentially deadly injuries. Medicine was crude, basically non-existent, and many died along the way.

Check out my latest Q&A on the Suspense Magazine Blog:

Could Death From Bleeding Be Delayed For Several Days After a Frontier Wagon Wheel Accident?

Read the answer and listen to the expanded audio information here:

http://suspensemagazine.com/blog2/2017/07/01/could-death-from-bleeding-be-delayed-for-several-days-after-a-frontier-wagon-wheel-accident/

This was one of the many clever questions included in my first Q&A book—MURDER & MAYHEM

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